Obstructive sleep apnea and atrial fibrillation are two conditions that share a potentially deadly link. Having one increases the odds of developing the other, and together, the breathing difficulties of sleep apnea combined with the irregular heartbeat of atrial fibrillation (AFib) can result in life-threatening cardiovascular risks.
The standard treatment for AFib is catheter ablation, a procedure in which doctors create scars within the heart to stop the electrical impulses that cause irregular heart rhythms.
But for decades, sleep apnea has been seen as an obstacle to ablation’s success, with studies showing that patients who suffer from both conditions often experience higher recurrence of AFib and poorer long-term outcomes.
Now, a new Tulane University study suggests that ablation still delivers major benefits for this high-risk group, significantly lowering the risks of heart failure and death for those diagnosed with sleep apnea and AFib.
The study, published in the Journal of Cardiovascular Electrophysiology, found that catheter ablation was associated with a 40% drop in major cardiovascular events and a 70% decline in all-cause mortality.
Catheter ablation was also associated with a decreased risk of blood clots that can block veins or arteries, causing an embolism or stroke.
Using data from the global TriNetX network, researchers followed outcomes from more than 18,000 patients, half of whom received catheter ablation and half of whom did not. The study was one of the most comprehensive analyses to date of the long-term benefits of catheter ablation in this high-risk population.
It's estimated that more than 40 million people worldwide have been diagnosed with AFib. It’s more difficult to calculate how many have sleep apnea, but one recent study estimated as many as 1 billion people may live with the condition.