A new study from LSU’s Pennington Biomedical Research Center shows that the brain’s preoptic area helps mice regulate their body weight, and that temperature-sensing nerve cells in that part of the brain could be used to curb weight gain.
The preoptic area (POA) is a small site critical to maintaining body temperature in warm-blooded animals, including humans, via temperature-sensing neurons. These nerve cells express the receptor for the hormone leptin, well-known for its effect on regulating body temperature and weight.